Vitamin B6 may reduce anxiety symptoms study shows
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Vitamin B6 may reduce anxiety symptoms study shows

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Vitamin B6 may reduce anxiety symptoms, study shows
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  • Researchers studied the impact of vitamins B6 and B12 to see how well either vitamin may work at reducing symptoms of anxiety and depression.
  • Study participants took high doses of their assigned vitamin for about a month.
  • Participants who took vitamin B6 saw a statistically significant reduction in anxiety symptoms, indicating improved functioning of GABA, the neurotransmitter associated with calming and relaxing.

Everyone may feel anxious or sad at times. However, some people may experience life-disrupting levels of these emotions on a regular basis, developing into a mental health disorder that requires treatment.

Researchers at the University of Reading in the United Kingdom studied how vitamin B6 and vitamin B12 may impact anxiety and depression levels.

Vitamins B6 and B12 are present in foods such as chickpeas and tuna, but the research team tested the vitamins at much higher levels than those found in food.

Mental health quick facts

Anxiety and mood disorders can affect people of all ages, from children to older adults. There are several types of disorders that fall under the umbrella of anxiety disorders, including panic disorder, generalized anxiety disorder, and social anxiety disorder.

According to the National Institute of Mental HealthTrusted Source (NIMH), around 31% of adults in the United States experience any anxiety disorder at some point in their lives. Additionally, around the same percentage of young adults (ages 13-18) experience an anxiety disorder.

The NIMHTrusted Source reports that around 8.4% of all adults in the U.S. experienced a depressive episode in 2020, making depression one of the most prevalent mental health conditions.

Medical providers often opt to treat anxiety and mood disorders with a combination of therapy and medications. Cognitive behavioral therapy and dialectical behavior therapy are two popular therapy options.

There are a number of prescription treatments for anxiety, including benzodiazepines (such as Xanax or Ativan) and buspirone. Also, certain antidepressants can help treat both anxiety and depression, which include SSRIs (such as Lexapro or Zoloft) and tricyclics (such as Anafranil or Tofranil).

People with anxiety and depression also occasionally try natural treatments to improve their symptoms and use herbal supplements such as ashwagandha and valerian

Large amounts of B6, B12

The researchers wanted to learn to what degree vitamins B6 and B12 can affect gamma-aminobutyric acid rusted Source (GABA) processing. GABA is a neurotransmitter that can calm the nervous system and may contribute to someone developing anxiety or depression.

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“The functioning of the brain relies on a delicate balance between the excitatory neurons that carry information around and inhibitory ones, which prevent runaway activity,” says Prof. David Field, lead author of the study and associate professor at the University of Reading’s School of Psychology and Clinical Language Sciences.

The inhibition-excitation balance being off in the brain has been linked to anxiety, depression, autism, and schizophrenia. Additionally, the authors write, that some people may experience visual and other sensory disturbances in many of these mental health conditions, “and these are thought to be related to excitation-inhibition imbalances in the visual cortex.”

According to the authors, “Vitamin B6 is involved in a number of other pathways that are likely to reduce neural excitation.” Vitamin B12 shares two of the same pathways, so the researchers wanted to test it as well to see what effect it would have.

The researchers recruited an initial group of 478 participants who had self-reported anxiety and/or depression. They were randomly chosen to receive vitamin B6, vitamin B12, or a placebo.

The B6 tablets contained 100 milligrams of B6, while the B12 tablets had 1,000 micrograms of B12. This far exceeded the daily dietary allowance recommended by the Food and Drug AdministrationTrusted Source, which is 1.7mg for B6 and 2.4mcg for B12.

The researchers screened the participants for anxiety and depression before and after the vitamin or placebo regimens using the Screen For Adult Anxiety Related Disorders (SCAARED) and Mood and Feelings Questionnaire (MFQ).

The researchers had the participants complete visual and tactile tests at the end of the trial.

The vitamin that helped

The study results indicated that vitamin B6 can be helpful in reducing anxiety and depression symptoms. The B6 participants saw a significant reduction in their SCAARED and MFQ tests compared to the placebo group.

“Vitamin B6 helps the body produce a specific chemical messenger that inhibits impulses in the brain, and our study links this calming effect with reduced anxiety among the participants,” says Prof. Field.

Additionally, in testing at the end of the trial, the B6 group showed an increase in “the surround suppression of visual contrast detection.” The authors write that this testing “argues for an inhibitory GABA-related underlying mechanism.”

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While the participants in the vitamin B12 group reported a slight improvement in anxiety and depression symptoms compared to the placebo group, the researchers did not consider it significant.

The authors noted that “it is possible that the 1-month supplementation period in the present study was insufficient for the effects of B12 supplementation.”

What the results mean

The study findings may be helpful to people with anxiety or depression in multiple ways.

First, vitamin B6 supplements are readily available over-the-counter at most drug stores and other retailers.

“This could be a breath of fresh air for people with anxiety disorders who have not had the options of new treatments for a long time,” Dr. Tom MacLaren, a consultant psychiatrist at Re: Cognition Health based in London, said in an interview with Medical News Today.

Another way the study may be helpful to people with anxiety or depression is that the findings indicate vitamin B6 may help with GABA.

“The authors highlight the role of vitamin B6 as a coenzyme in the synthesis of the inhibitory neurotransmitter GABA from glutamate,” Dr. David A. Merrill, a psychiatrist and director of the Pacific Neuroscience Institute’s Pacific Brain Health Center at Providence Saint John’s Health Center in Santa Monica, CA, told MNT.

“This makes sense and becomes an important way to explain the findings to patients and perhaps those who have not sought out treatment but are struggling with high anxiety,” he said.

Additionally, if some people with anxiety or depression are able to decrease symptoms using vitamin B6, they may be able to avoid the side effects of prolonged use of certain medications.

“Some anti-anxiety medications like benzodiazepines have potential side effects like sedation, imbalance, or memory loss,” Dr. Merrill continued. “Benzodiazepines can also be overused to the point of becoming ineffective, or you can develop both psychologic and physiologic dependence that makes it hard to stop using the drugs.”

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How to Use Turmeric for Skin Allergies

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How to Use Turmeric for Skin Allergies
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The golden spice turmeric has been used medicinally since ancient times. Curcumin, a therapeutic ingredient of turmeric, is mainly responsible for its health advantages. Curcumin possesses anti-inflammatory and antioxidant properties as a result of its chemical composition.

Although modern science is only beginning to investigate turmeric’s benefits, many people think it has a number of applications for the skin and allergies as well. The complexion may appear glowing and smooth because of these qualities. Likewise, people also think that turmeric can restore your skin’s natural radiance.

Curcumin, a powerful anti-inflammatory ingredient present in turmeric, helps to control allergy symptoms and reduce inflammation. You can use turmeric to cure moderate symptoms of allergic responses, though the best course of action relies on how severe your illness is. To discover if the herb benefits your allergies, you might want to give turmeric a shot at home. We are going to explore, the effectiveness of curcumin for allergies, how it acts, and its applications in depth here.

The Healing Power of Turmeric

The curcumin in turmeric can speed up the healing of wounds by reducing oxidation and inflammation. Additionally, it lessens how quickly your body reacts to skin wounds. Your injuries will heal more rapidly as a result. There have been many studies that show that turmeric helps collagen production and skin tissue tightening.

The publication Life Sciences advises the application of curcumin as part of an optimal formulation for treating skin sores. Curcumin also speeds up the process of wound healing since it encourages the creation of the growth factors necessary for wound healing. Therefore, you should regularly take the best turmeric supplement with black pepper if you suffer from skin allergies.

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The following are several ways that turmeric can help you manage your allergies. So, let’s take a look at some ways turmeric relieves allergies:

Helps in Curing Skin Problems

Turmeric’s anti-inflammatory and antioxidant properties may benefit your psoriasis by reducing flare-ups and other problems. According to the National Psoriasis Association, you can take it directly or as a supplement. The organization advises consulting a specialist about the right dosage before attempting it. If you want to lessen pimples and any resulting marks, you might want to give a turmeric facial mask a try. The anti-inflammatory properties can relax the skin and target your blackheads. Scarring is also thought to be lessened by turmeric. Your face may benefit from this mix of applications if you have skin problems.

If you want to lessen acne and scarring, you might want to give a turmeric face mask a try. The anti-inflammatory properties can relax the body and target your pores. There is also a belief that turmeric can help to reduce bruises. Your face may benefit from this mix of applications if you have skin problems. A herb called neem was combined with turmeric in an earlier trial to cure scabies. Scabies is a skin rash-producing disorder brought on by tiny parasites.

Research on turmeric’s potential to treat various skin problems is insufficient to draw firm conclusions. However, alopecia, eczema, lichen planus, as well as other skin conditions may benefit from its use. A study published in Therapeutic applications Research suggests more investigation into turmeric’s impact on various skin diseases. The study of turmeric as a skin remedy is gaining popularity.

Healthy For Asthma Patients

Turmeric can cure allergies and asthma; the polyphenolic flavonoid curcumin, a component of turmeric, can regulate your immune response and stop mast cells from releasing histamine, which causes an inflammatory reaction and itching.

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Helpful in Rhinitis

There’s also a way to treat allergic rhinitis with turmeric. Curcumin can help with sneezing, runny nose, and other allergic rhinitis issues. People with persistent seasonal allergies saw curcumin improve nasal circulation in a two-month study.

Beneficial For Itching

Therapeutic curcumin is a good anti-itching treatment, according to a mouse study. It might lessen itchiness brought on by histamine release. The capsaicin receptor was inhibited by curcumin in mouse nerve cells. The blistering and unpleasant feelings are caused by TRPV1 neurons.

Turmeric can assist in keeping your skin healthy when applied topically and when consumed orally. This herb possesses antibacterial and anti-inflammatory qualities. It aids in the treatment of several skin disorders, including vitiligo, alopecia, eczema, hypersensitivity, and pimples. But for the best and most immediate results, use turmeric curcumin with Bioperine, as it gets absorbed by blood faster.

Before We Part!

There is little preliminary evidence to back the utilization of turmeric or its main ingredient, curcumin, to cure allergies, despite its possible health advantages. As a result, ground turmeric has a long history of usage in herbal remedies and is healthy to use. The topical solutions that contain turmeric often have the advantage of being suitable for both adults and children. Before consuming turmeric supplements, always consult a medical practitioner.

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What is Modafinil?

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What is Modafinil
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A medicine that helps people feel more awake is called modafinil.

The extreme drowsiness brought on by sleep apnea, narcolepsy, or working nights sleep disorder can be treated via buying or order modafinil.

In addition to the uses described in this medication guide, modafinil may also be utilized for various other functions.

Cautions

If you have ever had any kind of skin rash or allergic response while using modafinil or armodafinil, you should avoid it (Nuvigil).

Skin responses have been linked to the use of modafinil, and some of these reactions may be severe enough that they need medical attention in a hospital setting. If you develop symptoms such as a rash, hives, blisters, peeling skin, mouth sores, difficulty swallowing or breathing, fever, swelling in your legs, dark urine, yellowing skin or eyes, or swelling in your face, you should immediately stop taking this medication and seek emergency medical attention.

You Must Read This Before Taking This Medicine

Do not use this medication if you have ever had an adverse response to modafinil or armodafinil, including but not limited to a skin rash (Nuvigil).

Telling your doctor if you have any of the following conditions can ensure that buy modafinil is a safe choice for you to take:

  • chest pain is known as angina;
  • cirrhosis or another kind of liver disease;
  • kidney disease;
  • hypertension, cardiovascular disease, or a family history of heart attacks;
  • a family history of schizophrenia or another mental disorder; or
  • previous struggles with alcoholism or drug addiction.

It is unknown whether or not this medication may cause damage to a developing baby if used during pregnancy. You should consult your doctor if you are pregnant or trying to get pregnant.

Before ordering modafinil, there is some evidence that decreases the effectiveness of several birth control methods. During treatment, you may be unable to rely on hormonal contraception (including tablets, injections, implants, skin patches, and vaginal rings) to prevent you from becoming pregnant. While using modafinil, it is important to discuss with your healthcare provider the most appropriate forms of birth control for you.

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It is unknown if modafinil is excreted into breast milk or whether it may be harmful to a baby who is being breastfed. If you are breastfeeding a child, you should let your doctor know about it.

It is illegal for anybody less than 17 years old to take the wakefulness-promoting drug modafinil.

The best way to take modafinil

Always be sure to follow all of the instructions on the label of your medication. It is not safe to use modafinil in higher or lower doses or for a more extended period of time than what is indicated. Modafinil will likely become addictive. Never, ever give modafinil to another individual, particularly someone who has a history of abusing drugs or developing an addiction. Keep the medicine in a secure location that will not be accessible to anybody else. It is against the law to sell or distribute modafinil in any form. To avoid being sleepy throughout the day, you should take modafinil first thing in the morning. If you need to address sleep disturbances during the workday, you should take it an hour before your shift begins. It would be best if you read all the patient information, prescription guidelines, and instruction sheets sent to you. If you have any questions, you should ask your doctor or pharmacist. Either with or without the meal is OK when taking modafinil.

In most cases, the duration of modafinil treatment is no more than 12 weeks. When treating drowsiness brought on by obstructive sleep apnea, a CPAP machine may be utilized in addition to modafinil. While you are sleeping, this device, which consists of an air pump coupled to a mask, will push pressured air into your nose in a gentle manner. Although the pump cannot breathe for you, its mild push of air may assist in keeping your airway clear and preventing blockage. If your doctor has not instructed you to cease using your CPAP machine while you sleep, you should continue to do so. The most effective therapy for your issue would be a mix of using a CPAP machine and taking modafinil. Modafinil will not address the underlying causes of obstructive sleep apnea, nor will it heal the condition itself. Always be sure to follow the advice given to you by your doctor for any further therapies for this condition. Even when taking modafinil, you should see your physician if you are still experiencing extreme drowsiness. Taking modafinil is not a replacement for obtaining the recommended sleep each night. Keep at room temperature and away from heat and moisture while storing. Maintain a record of the quantity of medication consumed from each fresh bottle. Because modafinil is a substance that may lead to addiction, you need to be aware if somebody is misusing your medication or taking it without a prescription.

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Author: Dr. Pulakhandam graduated from the Mahadevappa Rampure Medical College in 1993. She works in Pensacola, FL and 4 other locations and specializes in Child and Adolescent Psychiatrist, Psychiatry and Adult, Child/Adolescent Psychiatry. Dr. Pulakhandam is affiliated with Lake Charles Memorial Hospital and West Florida Hospital.

 

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Finding the Right Coupons for Meal Time

Madison Franz

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Finding the Right Coupons for Meal Time
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A family meal plan isn’t complete without coupons. Coupons are savings you have to seek out, so they reward intrepid planners by slashing the costs of a variety of different foods. Coupons aren’t limited to the grocery store, either. Many takeout and delivery options have coupons that can provide an affordable and tasty meal on busy nights. From complete takeout feasts to mix and match pizza deals, here’s how to find the best coupons for your family’s needs.

The Power of Coupons

Are coupons really a better deal? The answer is a resounding yes. That’s because of the secret of coupons: Most of the restaurant’s customers don’t look for them or use them, opting to simply pay full price. This allows savvy meal planners to cash in on discounts that chains and restaurants can’t offer on every single order without losing money.

The Value in the Product

When considering your dinner and coupon options, it’s tempting to look at the total cost above all else. However, the total is only half of the equation when it comes to making dinner decisions. You also have to look at the value of what you’re getting for that amount.

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For example, coupons for a small fast-food family dinner may total less than other options, but what are you receiving for that price? Can you use the dinner for leftovers? Is there a vegetable anywhere in sight? Probably not.

Papa Johns coupons, on the other hand, provide enough food for leftovers and are made from quality ingredients. Good pizza will survive a few nights in the fridge or half a day in a lunchbox. Look for deals that you can get more than one meal out of and foods that are made from filling ingredients.

Where To Find Coupons

To find current coupons for premade dinners, it’s best to check a variety of sources. Some of these include:

  • Paper coupons delivered weekly in the mail
  • The ‘coupons’ section of a restaurant’s website
  • Searching Google for a restaurant’s name plus the word ‘coupons’
  • Downloading a restaurant’s app to your phone
  • Following a restaurant on social media
  • Joining a restaurant’s loyalty program or mailing list
  • Using a coupon-finding browser extension such as Honey
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Remember that coupons and deals are always changing, so check frequently for deals that will suit your family. One advantage of using coupons over other food cost-cutting methods is variety. With rotating deals, your family won’t be stuck eating the same meal week after week.

Meals for Your Family

One of the biggest daily stressors for many families is what to serve for dinner. Coupons are an important tool to make this decision easier.

Remember that what you’re getting out of the deal is as important as the price on the coupon. Think beyond the grocery store checkout aisle and use coupons to make the occasional takeout meal an affordable treat that takes the pressure off of the cooks in the family. After all, free pizza is a dinner even the pickiest eaters can agree on.

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